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What makes smoking weed mixed with heavy metals even more dangerous is that these metals can stay in the body for years after the exposure ends

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Nicotine binds specific acetylcholine receptors, mostly neuronal nicotinic acetylcholine receptors (nAChRs) 42 subtypes, in the central nervous system, and stimulates the release of neuromodulators (mainly dopamine) promoting pleasure and thus perpetuating consumption [13]